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Hyperthyroidism and Pregnancy

Hyperthyroidism and Pregnancy

To review:

  • Changes in thyroid economy during pregnancy
  • Thyroid function tests in pregnancy
  • Hyperthyroidism and pregnancy
  • During pregnancy
  •         Basal                                                                                                150
  •         40-50 % increased T4 requirements                                  50-100
  •          transfer of T4 and I from mother to fetus                           50
  •          Increased renal clearance of I                                               ?
  •                                                                                                                250-300
  • During lactation
  •          Basal                                                                                      150
  •          0.5-1.1 L milk/day x 150-180 mgI/L                                  75-200
  •                                                                                                                225-350
  • Neonate and young infant
  •         Term 15 mg/kg/day      )
  •         Preterm 30 mg/kg/day) x 3-6 kgs                                           90
  • Delange: Int J Endocrinol Metab 2: 1, 2004                         
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